Researchers Discovered New Compound Killing both Gram +ve and Gram-ve Bacteria
Antimicrobial resistance leads to development of Superbugs. Drug résistance by microorganisms is challenging to the scientists and drive them to discover new and new chemical substances. Genetic mutation a major reason for Antimicrobial resistance has widened the horizons of research and the researchers studying the cellular mechanisms working on discovering novel anti-microbial agents.
Most of the microbial infections are being caused by Bacteria and by virtue of their cellular composition, they may be Gram positive or Gram negative. Due to an outer lipid membrane the Gram-negative bacteria it is some what difficult to treat such bacterial infections. As a matter of fact, majority of the anti-microbial agents which are effective on Gram positive bacteria does not exhibit significant effect on Gram negative bacteria.
Researchers at the University of Sheffield, UK have developed a new broad-spectrum luminescent compound which is able to kill both gram-positive and gram-negative antibiotic-resistant bacteria. An underlying mechanism for such unique activity of this compound is that it passes through the cell wall of both kinds of bacteria and trigger its action at bacterial DNA.
This discovery paves a way for development of new treatments for all kinds of antibiotic resistant bacteria and surely helpful the un-met needs.
